Hydrogen H2 Inhalation Therapy Introduction

These guides set the criteria for devices used in hydrogen inhalation therapy.



Recent attention has focused on a technology that separates hydrogen gas by combining it with other materials on Earth, given the industry’s interest in the hydrogen economy. ‘By-product hydrogen,’ ‘natural gas reforming,’ and ‘water electrolysis’ are the three most common technologies for producing hydrogen. The water electrolysis method, used for breathing and medical purposes, is one of these.

Two types of water electrolysis exist an alkaline and a polymer electrolyte method. Both generate hydrogen by electrolyzing water. The polymer electrolyte (PEM) method, suitable for breathing, generates the cleanest hydrogen using pure platinum and titanium catalysts to separate sterilized distilled water without any electrolysis catalyst additives. It’s more expensive than other methods but suitable for medical and respiratory purposes.

On the contrary, the alkaline electrolyte method, an older technology, electrolyzes water after injecting sodium hydroxide (NaOH) or potassium hydroxide to boost gas generation. It then supplies the hydrogen through a gas filter for electrolyte management.

The purpose of hydrogen inhalation is health maintenance, so cleanliness is vital. Hydrogen generators used for industrial purposes are unsuitable for breathing. Therefore, devices for therapeutic purposes should use ‘polymer electrolyte water electrolysis system’ technology to separate hydrogen gas, even if it’s expensive.


Most hydrogen generators were initially for industrial use, and medical devices have just started to appear. As previously mentioned, the hydrogen separation technology of people’s devices for treatment must use a polymer electrolyte method. It must be additive-free and generated cleanly. Also, it must have a structure where the hydrogen-to-oxygen ratio is 2:1 (66.66% hydrogen, 33.33% oxygen). The volume generated per minute must be between 1,200 and 1,450cc (high concentration). Lastly, the device must work continuously for more than 8 hours without causing issues with the equipment’s life. All these conditions are necessary for those seeking treatment or health.

In molecular hydrogen inhalation, you insert a nasal cannula (or nasal cord) into a generator’s nose and inhale gaseous hydrogen and oxygen. If you discard oxygen and inhale only hydrogen, you might not get enough oxygen when breathing. The nasal cannula reduces the nostril area, leading to less inhalation than natural breathing. Thus, inhaling the separated hydrogen and oxygen would be best without discarding them.

On average, adults at rest breathe 12 to 20 times per minute, inhaling about 270 to 460 cc each time, totaling 5,400 to 9,200 cc daily. However, exhaling takes almost twice as long as inhaling. Breathing varies greatly depending on a person’s physique, constitution, and old habits.

When humans breathe, they inhale 78% nitrogen, 21% oxygen, 0.04% carbon dioxide, and 0.6% other substances. Oxygen constitutes 21% of inhaled in one breath, or 1,134 to 1,934cc per minute. However, if the nasal cannula’s hose thickness reduces the nostril area, you’ll naturally breathe less than usual. Hence, it’s correct to supply oxygen through a nasal cannula, the generator standard in Japanese hospital emergency rooms.

‘How much hydrogen should I inhale?’ According to clinical trial standards in Japan and the United States, the higher the hydrogen inhalation content, the greater the effect. However, a clinical trial in Japan gave patients who received artificial respiration after CPR 98% oxygen (O2) and 2% hydrogen (H2) to inhale hydrogen for up to 18 hours. But, this refers to a case where only 98% oxygen and 2% molecular hydrogen stored in a tank are inhaled together with oxygen through an airtight mask without spontaneous breathing. When molecular hydrogen is inhaled through a nasal cannula with water electrolysis from the polymer electrolyte method, the hydrogen’s specific gravity must be increased.


You should avoid devices that use materials reacting with hydrogen, oxygen, and water, like various hoses and pipes where water or gas passes inside the hydrogen generator. However, as the general public may find this hard to understand, you should choose a product with a “hazardous substance safety certification,” ensuring that the product materials or composition don’t change.


Firstly, the more molecular hydrogen you inhale, the better the effect. For healthy people, 2 hours or more a day for prevention and immunity management, 4 hours or more a day for the elderly or chronic diseases, 5 hours or more a day for cancer treatment, 6 hours or more a day for brain diseases such as Parkinson’s or lung diseases are recommended. If you inhale for a long time, using it while sleeping at night is better.

Unlike other treatments, you should integrate molecular hydrogen inhalation into your life, even when healthy or recovered. It should be part of your daily routine, like exercise or eating, for immunity management, virus prevention, and treatment in aging or chronic disease cases. Read more…


If the cannula tube’s accumulated moisture turns into water and enters the nose; you should be careful. This is a primary concern, especially when inhaling hydrogen while sleeping. Water should not enter the nose through the nasal cannula even if the device runs for 8 hours continuously, based on an 8-hour sleep. If water droplets enter the nose while sleeping, it interrupts sleep, and sometimes water enters the throat, requiring special attention. Read more…

When most devices run for more than 3 hours in a row, the nasal cannula gets damp, and the moisture cools down, causing water droplets to enter the nose. In this case, you should use a new nasal cannula or discontinue inhalation therapy. When choosing equipment, select one that does not allow water to enter your nose, even if you operate it for a long time.